In a game of Endeavor you basically throw down your population markers to represent places you’re shipping to. This allows you to grab trade tokens that have symbols on them allowing you to advance along one of the four status tracks. Advancing along the tracks gets you more stuff and points.
Population markers in an area means you have presence there. Now you can take the draw (crate) action that allows you to pick up cards that have more symbols on them adding to your advancement on the tracks.
It’s a game of careful placement on the board of your population markers based on your strategy and what your opponents are doing. As you advance along the status tracks you’re not going to be able to advance all four of them equally well. You have to pick one to lag behind the others. Lots of good strategy choices in this game and it’s important to pay attention to what your opponents are doing.